CD200 antibody (APC)

Catalog No. ABIN7672808

This Rat Monoclonal antibody specifically detects CD200 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for CD200 antibody (APC) (ABIN7672808)

Target: CD200

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD200 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: OX-90

Product Details anti-CD200 Antibody (APC)

Purpose: APC Anti-Mouse CD200/OX2 Antibody

Purification: 0

Purity: 0

Isotype: IgG2a, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CD200

Target: CD200

Alternative Name: CD200

Background:

Synonyms: MRC|OX-2|OX-2 membrane glycoprotein

Background: CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, B cells, and brain tissue (neurons), but not on NK cells, granulocytes, monocytes, or macrophages. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. CD200 is the ligand for CD200 receptor (CD200R). The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity. Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation.

Molecular Weight: 0

Gene ID: 4345

UniProt: O54901